Bromosporine

性能参数

产品名称

Bromosporine

规格

5mg  10mg 50mg

货号

GOY-Y3978

 含量

>98.00%

CAS

1619994-69-2

别名

化学名

ethyl (3-methyl-6-(4-methyl-3-(methylsulfonamido)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-yl)carbamate

分子式

C17H20N6O4S

分子量

分子量 404.44

溶解度

≥ 40.4 mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Bromosporine is a broad spectrum inhibitor of bromodomains with IC50 value of 0.41 μM, 0.29μM, 0.122μM for BRD2, BRD4 and BRD9, respectively [1].

Bromodomains is a 110 amino acid protein domain which can recognize monoacetylated lysine residues and play a pivotal role in the targeting of chromatin-modifying enzymes to specific sites. It has been revealed that proteins contained BRDs involves in the development of many diseases, including cancers, inflammatory diseases and neurological diseases.

It is also reported that Bromosporine functioned on BAZ2A, BRPF3, CECR2, FALZ and TIF-1α with IC50 value of 9.36μM, 48.11μM, 0.017μM, 5.655μM and 12.38μM, respectively [1].

cis-紫茎女贞苷B ;cis- Lig 规格： 10mg

紫茎女贞苷D ;Ligupurpuros 规格： 10mg

紫茎女贞苷C;Ligupurpurosi 规格： 10mg

紫茎女贞苷B;Ligupurpurosi 规格： 10mg

紫茎女贞苷A ;Ligupurpuros 规格： 10mg

肉碱; L(-)-Carnitine 规格： 20mg

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